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Rectal administration uses the rectum as a route of administration for medication and other fluids, which are absorbed by the rectum's blood vessels[Note 1] and flow into the body's circulatory systemwhich distributes the drug to the body's organs and bodily systems. A drug that is administered rectally will in general depending on the drug have a faster onset, higher bioavailabilityshorter peak, and shorter duration than oral administration. In addition, the rectal route bypasses around two thirds of the first-pass metabolism as the rectum's venous drainage is two thirds systemic middle and inferior rectal vein and one third hepatic portal system superior rectal vein.

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This leaflet gives tips about how to give rectal medicines suppositories and enemas to children. This leaflet has been written specifically about the use of medicines in children. Please read this leaflet carefully.

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Sufficient fibre intake is one of the hallmark recommendations for a healthy diet. However, it is possible to have too much of a good thing. If you regularly consume large amounts of fibre, you may find yourself experiencing an unpleasant sensation known as perianal itching, or itching in the area around the anus.

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Hemorrhoids are uncomfortable swollen veins in the rectum or anus. Internal hemorrhoids swell inside the anus, and external hemorrhoids swell near the opening of the anus. During a bowel movement, the anal tissue swells with blood to help control movement. When hemorrhoids occur, the anal tissue experiences increased pressure that causes excessive swelling and stretching.

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An anal fissure is a small tear in the lining of the anal canal, just inside the opening. It is associated with spasm of the lower portion of internal anal sphincter muscle the 'automatic door closer' abnormally raising the pressure in the lower portion of the anal canal. This increased pressure reduces the blood flow to the base of the fissure, prohibiting healing.

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An alcohol enemaalso known colloquially as butt-chugging or boofingis the act of introducing alcohol into the rectum and colon via the anus. This method of alcohol consumption can be dangerous and even deadly because it leads to faster intoxication since the alcohol is absorbed directly into the bloodstream and neutralizes the body's ability to reject the toxin by vomiting. Two reported techniques specific to alcohol enemas are via an alcohol-soaked tampon and via a funnel, such as a beer bonginserted into the rectum.

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Life is all about the little joys: getting a free cup of coffee from a waiter, finishing the Sunday morning puzzle, a stranger giving you a friendly smile on the train ride home. One of these little joys is a good bowel movement. You usually get off the toilet feeling lighter and brighter than you did going in, and it puts that little extra pep in your step you need to get through the day.

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